Breast-cancer screening with mammography in women aged 40–49 years

✍ Scribed by Organizing Committee; Collaborators; Falun Meeting; Falun; Sweden

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: French
• Weight: 670 KB
• Volume: 68
• Category: Article
• ISSN: 0020-7136
• DOI: 10.1002/(sici)1097-0215(19961211)68:6<693::aid-ijc1>3.0.co;2-z

✦ Synopsis

For some years, there has been a perceived need for more information on the effect of screening for breast cancer in women aged 40 to 49. Our approach was to gather the most recent data on screening in this age group, to assess the following quantities: the likely beneffi in mortality terms, measures of screening performance and arrest of tumour progression through screening, costs and public-health implications, and prospects for future screening and research. A collaborative meeting was held in Falun, Sweden, for which data were gathered in advance from all the randomized trials of breast-cancer screening that included women in this age group, and all identifiable substantial databases on service screening of women aged 40 to 49. Updated results from the Swedish overview of mammographic screening trials indicated relative mortality associated with invitation to screening of 0.77 (95% confidence interval 0.59-1.01). Combining all population-based randomized trials gave the relative-mortality figure of 0.76 (0.62-0.93), and combining all trials gave 0.85 (0.7 I-I .O I). Relative-mortality figures in individual trials could be predicted by the rates of advanced cancers in those trials. Detailed analysis suggested faster tumour progression in the age group 'Names and affiliations of the committee members and the collabo-(and control group in the case of trials), atten B ance rates, rators are listed in the appendix.