## Abstract Estrogen has been suggested to trigger breast cancer development via an initiating mechanism involving its metabolite, catechol estrogen (CE). To examine this hypothesis, we carried out a multigenic caseβcontrol study of 469 incident breast cancer patients and 740 healthy controls to de
Breast cancer risk associated with genotypic polymorphism of the genes involved in the estrogen-receptor-signaling pathway: a multigenic study on cancer susceptibility
β Scribed by Jyh-Cherng Yu; Huan-Ming Hsu; Shou-Tung Chen; Giu-Cheng Hsu; Chiun-Sheng Huang; Ming-Feng Hou; Yi-Ping Fu; Ting-Chih Cheng; Pei-Ei Wu; Chen-Yang Shen
- Publisher
- BioMed Central
- Year
- 2006
- Tongue
- English
- Weight
- 232 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1021-7770
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Aneuploidy, an abnormal number of chromosomes, is relatively common and occurs early in breast cancer development. This observation supports a breast tumorigenic contribution of mechanisms responsible for maintaining chromosome number stability in which centrosomes play an essential rol
## Abstract Menopausal hormone therapy (HT) is associated with increased breast cancer risk among postmenopausal women. Nuclear receptors are involved in steroid hormoneβ and xenobioticβmediated signal transduction playing a crucial role in regulating gene expression. Therefore, variations within t
## Abstract Common germline genetic variation in the population is associated with susceptibility to epithelial ovarian cancer. Microcellβmediated chromosome transfer and expression microarray analysis identified nine genes associated with functional suppression of tumorogenicity in ovarian cancer