Cyclin D1 gene amplification and overexp
Cyclin D1 gene amplification and overexpression are present in ductal carcinomain situ of the breast
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Vos, Carla B. J.; ter Haar, Natalja T.; Peterse, Johannes L.; Cornelisse, Cees J
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Article
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1999
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John Wiley and Sons
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English
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Cyclin D1 (CCND1) amplification is found in 10-15 per cent of invasive breast carcinomas, but it is not well established whether this gene alteration also occurs in the precursor of invasive breast carcinoma, ductal carcinoma in situ (DCIS). By Southern blot analysis, cyclin D1 gene amplification wa