Osteolytic and osteoblastic metastases are often the cause of considerable morbidity in patients with advanced prostate and breast carcinoma. Breast carcinoma metastasis to bone occurs because bone provides a favorable site for aggressive behavior of metastatic cancer cells. A vicious cycle arises b
β¦ LIBER β¦
BREAST-CANCER OSTEOLYSIS, BONE METASTASES, AND ANTI-OSTEOLYTIC EFFECT OF ASPIRIN
β Scribed by Powles, T.J.; Dowsett, M.; Easty, G.C.; Easty, D.M.; Neville, A.M.
- Book ID
- 122568570
- Publisher
- The Lancet
- Year
- 1976
- Tongue
- English
- Weight
- 382 KB
- Volume
- 307
- Category
- Article
- ISSN
- 0140-6736
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## Abstract Most breast cancer metastases in bone form osteolytic lesions, but the mechanisms of tumorβinduced bone resorption and destruction are not fully understood. Although it is well recognized that Wnt/Ξ²βcatenin signaling is important for breast cancer tumorigenesis, the role of this pathway
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