## Abstract The relative frequency of lymphocytes with surface immunoglobulins (sIgM, sIgG, sIgA) was studied in breastโcancer patients' axillary lymph nodes by the immunofluorescence technique. The study encompassed a total of 105 patients, most of whom had infiltrating ductal carcinoma (IDC). The
Breast cancer metastasis and lymph node lymphocyte-macrophage interaction
โ Scribed by Dr. Arnis Richters
- Book ID
- 102434659
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 222 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0022-4790
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โฆ Synopsis
Abstract
A lymphocyteโmacrophage interaction, known as the lymphocyte clustering phenomenon, was studied in axillary lymph node preparations from 27 breast cancer patients. The study was carried out in primary tissue cultures of lymph nodes and the lymphocyteโmacrophage interactions were quantitated with respect to cancer positive and cancer negative axilla. The results indicate that there is a significantly higher (p< 0.025) lymphocyteโmacrophage interaction in negative node preparations from negative axilla of infiltrating ductal carcinoma patients. This new approach to lymph node lymphocyte evaluation may provide assistance in determining the extent of the disease process.
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