Breast Cancer Epidemiology

✍ Scribed by Jacques Ferlay, Clarisse Héry, Philippe Autier (auth.), Christopher Li (eds.)

• Publisher: Springer-Verlag New York
• Year: 2010
• Tongue: English
• Leaves: 417
• Edition: 1
• Category: Library

✦ Synopsis

As the most common cancer diagnosed among women world-wide, breast cancer is a disease of considerable public health importance. The number of established and hypothesized risk factors for breast cancer exceeds that of any other cancer resulting in a rich, but complicated and often conflicting literature on the epidemiology of this disease. Our understanding of factors that contribute to breast cancer risk, as well as the biology and molecular basis for this common disease, has greatly increased over the past few decades. This book provides a comprehensive review and critical assessment of the epidemiology literature on all major aspects of breast cancer incidence and mortality, etiology, and outcomes. Chapters are written by internationally recognized leaders in the field and provide a timely review of traditional etiologic risk factors, as well as more recently evaluated exposures. Several chapters are also devoted to clinical aspects of breast cancer including screening, diagnosis and treatment, and survival. As a result, this is the most up-to-date and comprehensive book on breast cancer epidemiology available.

✦ Table of Contents

Front Matter....Pages i-xiii
Global Burden of Breast Cancer....Pages 1-19
Breast Cancer Biology and Clinical Characteristics....Pages 21-46
In situ Breast Cancer....Pages 47-72
Endogenous Hormones....Pages 73-87
Exogenous Hormones....Pages 89-117
Reproductive Factors....Pages 119-135
Physical Activity and Anthropometric Factors....Pages 137-151
Diet and Nutrition....Pages 153-181
Environmental and Occupational Exposures....Pages 183-221
Shift Work and Circadian Disruption....Pages 223-241
Non-Hormonal Medications and Chronic Diseases....Pages 243-260
Male Breast Cancer....Pages 261-276
Inherited Predisposition: Familial Aggregation and High Risk Genes....Pages 277-299
Common Genetic Susceptibility Loci....Pages 301-320
Mammographic Density as a Potential Surrogate Marker for Breast Cancer....Pages 321-341
Breast Cancer Screening....Pages 343-369
Principles of Breast Cancer Therapy....Pages 371-388
Breast Cancer Outcomes....Pages 389-401
Back Matter....Pages 403-417

✦ Subjects

Cancer Research; Human Genetics; Laboratory Medicine; Medical Microbiology; Molecular Medicine; Virology