Barriers to nonviral gene delivery
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Christopher M. Wiethoff; C. Russell Middaugh
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Article
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2003
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John Wiley and Sons
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English
β 166 KB
The use of various synthetic lipids and polymers to deliver DNA for gene therapy applications has been the subject of intense examination for the last 15 years. Our understanding of the processes involved in the delivery of DNA, although still limited, can be described in terms of specific physical