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Breakage-Fusion-Bridge Cycles Causing Chromosome Instability in Human Cleavage Stage Embryos

✍ Scribed by Philippos C. Patsalis


Book ID
102260683
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
70 KB
Volume
32
Category
Article
ISSN
1059-7794

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✍ Thierry Voet; Evelyne Vanneste; Niels Van der Aa; Cindy Melotte; Sigrun Jackmaer 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 633 KB

Recently, a high incidence of chromosome instability (CIN) was reported in human cleavage stage embryos. Based on the copy number changes that were observed in the blastomeres it was hypothesized that chromosome breakages and fusions occur frequently in cleavage stage human embryos and instigate sub