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BRCA2, but not BRCA1, mutations account for familial ovarian cancer in Iceland: a population-based study

✍ Scribed by Thorunn Rafnar; Kristrun R. Benediktsdottir; Bjarki J. Eldon; Thorgeir Gestsson; Hafsteinn Saemundsson; Karl Olafsson; Anna Salvarsdottir; Eirikur Steingrimsson; Steinunn Thorlacius

Book ID: 116428363
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 255 KB
Volume: 40
Category: Article
ISSN: 0959-8049
DOI: 10.1016/j.ejca.2004.09.008

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## Abstract Our aim was to estimate the prevalence of mutations in the __BRCA1__ and __BRCA2__ genes among unselected incident cases of breast cancer in young women. We identified 158 incident breast cancer cases diagnosed before age 46 years in predefined geographic areas in Girona and Tarragona,