𝔖 Bobbio Scriptorium
✦   LIBER   ✦

BRCA2 and Smad3 synergize in regulation of gene transcription

✍ Scribed by Preobrazhenska, Olena; Yakymovych, Mariya; Kanamoto, Takashi; Yakymovych, Ihor; Stoika, Rostyslav; Heldin, Carl-Henrik; Souchelnytskyi, Serhiy


Book ID
110066892
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
253 KB
Volume
21
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Identification of the gene transcription
✍ Jian Yu; Liang Zhang; Ailiang Chen; Guangxin Xiang; Yahui Wang; Jianping Wu; Kei 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 416 KB

## Abstract Transforming growth factor‐β (TGF‐β) signaling is known to depend on the formation of Smad2/3‐Smad4 transcription regulatory complexes. However, the signaling functions of Smad2/3‐Smad4 during TGF‐β‐induced responses are obscure as TGF‐β also initiates a number of other signaling pathwa

Transcriptional regulation of Smad2 is r
✍ Steven A. Johnsen; Malayannan Subramaniam; Takenobu Katagiri; Ralf Janknecht; Th 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 178 KB

TGFbeta inducible early gene (TIEG) is a novel Krüppel-like transcriptional repressor that was recently shown to increase the activity of the TGFbeta/Smad signal transduction pathway by relieving negative feedback through repression of the inhibitory Smad7. Interestingly, while Smad7 is required for

Emerging roles of BRCA1 in transcription
✍ Yumay Chen; Wen-Hwa Lee; Helen K. Chew 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 206 KB 👁 2 views

BRCA1 was the first breast cancer susceptibility gene to be identified and cloned. In individuals from high-risk families, mutations in BRCA1 increase the lifetime risk of developing breast cancer eight to tenfold, compared to the general population. How the BRCA1 protein product normally functions