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BRCA1 transcriptionally regulates genes associated with the basal-like phenotype in breast cancer

✍ Scribed by Julia J. Gorski; Colin R. James; Jennifer E. Quinn; Gail E. Stewart; Kieran Crosbie Staunton; Niamh E. Buckley; Fionnuala A. McDyer; Richard D. Kennedy; Richard H. Wilson; Paul B. Mullan; D. Paul Harkin

Publisher
Springer US
Year
2009
Tongue
English
Weight
702 KB
Volume
122
Category
Article
ISSN
0167-6806

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## Abstract Breast cancer is a common malignancy with current biological therapies tailored to steroid hormone (ER, PR) and HER2 receptor status. Understanding the biological basis of resistance to current targeted therapies and the identification of new potential therapeutic targets is an ongoing