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BRCA1 regulation of the mitotic checkpoint proteins underlying Taxol-resistance in human breast cancer

โœ Scribed by W. Y. Chung; A. McGoldrick; E. Gallagher; B. Flynn; M. J. Kerin; P. A. Dervan; A. McCann

Publisher
Springer-Verlag
Year
2005
Tongue
English
Weight
187 KB
Volume
174
Category
Article
ISSN
1863-4362

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The protein tyrosine phosphatase SHP-1 is predominantly expressed in hemopoietic cell lineages, where its function is relatively well defined. However, its expression profile also extends to certain epithelial cell types. Furthermore, the negative regulatory role of this enzyme in hemopoietic cell s