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BRCA1 induces DNA damage recognition factors and enhances nucleotide excision repair

✍ Scribed by Hartman, Anne-Renee; Ford, James M.


Book ID
109919802
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
533 KB
Volume
32
Category
Article
ISSN
1061-4036

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Critical DNA damage recognition function
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## Abstract It has been reported that 80–90% of human cancers may result, in part, from DNA damage. Cell survival depends critically on the stability of our DNA and exquisitely sensitive DNA repair mechanisms have developed as a result. In humans, nucleotide excision repair (NER) protects the DNA a