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BRCA1 expression is not directly responsive to estrogen

✍ Scribed by Marks, Jeffery R; Huper, Gudrun; Vaughn, James P; Davis, Penelope L; Norris, John; McDonnell, Donald P; Wiseman, Roger W; Futreal, Andrew; Iglehart, J Dirk

Book ID
110060474
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
548 KB
Volume
14
Category
Article
ISSN
0950-9232

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## Abstract The breast cancer susceptibility genes __BRCA1__ and __BRCA2__ are responsible for a large proportion of familial breast and ovarian cancer, yet little is known of how disruptions in the functions of the proteins these genes encode increased cancer risk preferentially in hormone‐depende