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BRCA1 and GADD45 mediated G2/M cell cycle arrest in response to antimicrotubule agents

โœ Scribed by Mullan, Paul B; Quinn, Jennifer E; Gilmore, Paula M; McWilliams, Stewart; Andrews, Heather; Gervin, Celine; McCabe, Nuala; McKenna, Sarah; White, Pat; Song, Young-Han

Book ID
110065959
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
316 KB
Volume
20
Category
Article
ISSN
0950-9232

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GADD45b and GADD45g are cdc2/cyclinB1 ki
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โœ Mariappan Vairapandi; Arthur G. Balliet; Barbara Hoffman; Dan A. Liebermann ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 415 KB

## Abstract Gadd45a (Gadd45), Gadd45b (MyD118), and Gadd45g (CR6) constitute a family of evolutionarily conserved, small, acidic, nuclear proteins, which have been implicated in terminal differentiation, growth suppression, and apoptosis. How Gadd45 proteins function in negative growth control is n