BRCA1 and BRCA2 gene mutations and risk of breast cancer:: Public health perspectives
β Scribed by Steven S Coughlin; Muin J Khoury; Karen K Steinberg
- Book ID
- 117571414
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 104 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0749-3797
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## Abstract Although there are several plausible biologic mechanisms whereby coffee consumption might influence the risk of breast cancer, epidemiologic evidence is limited. We assessed the association between coffee consumption and breast cancer risk among highβrisk women who carry __BRCA__ mutati
We have screened index cases from 25 Russian breast/ovarian cancer families for germ-line mutations in all coding exons of the BRCA1 and BRCA2 genes, using multiplex heteroduplex analysis. In addition we tested 22 patients with breast cancer diagnosed before age 40 without family history and 6 patie