The recent discovery of the breast cancer-associated genes BRCA1 and BRCA2 has changed the clinical care provided to women at high risk of breast cancer. We will review what is currently known about the clinical management of patients who bear (or are suspected of bearing) mutations in either of the
โฆ LIBER โฆ
BRCA-associated cancer risk: Molecular biology and clinical practice
โ Scribed by Kenneth van Gole; Kara Milliron; Seena Davies; Sofia D Merjver
- Book ID
- 114054161
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 879 KB
- Volume
- 134
- Category
- Article
- ISSN
- 1532-6543
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Clinical management of BRCA1- and BRCA2-
โ
Stephen E. Karp
๐
Article
๐
2000
๐
John Wiley and Sons
๐
English
โ 115 KB
๐ 2 views
Cancer and genes: how will molecular bio
โ
B.A.J. Ponder
๐
Article
๐
1997
๐
Elsevier Science
๐
English
โ 476 KB
The APC I1307K Allele and BRCA-Associate
โ
Diane L. Maresco; Patricia H. Arnold; Yukio Sonoda; Mark G. Federici; Faina Bogo
๐
Article
๐
1999
๐
American Society of Human Genetics
๐
English
โ 94 KB
Breast cancer risk associated with BRCA1
โ
Fackenthal, James D.; Olopade, Olufunmilayo I.
๐
Article
๐
2007
๐
Nature Publishing Group
๐
English
โ 504 KB
Molecular characterization and cancer ri
โ
A. A. Tesoriero; E. M. Wong; M. A. Jenkins; J. L. Hopper; kConFab; M. A. Brown;
๐
Article
๐
2005
๐
John Wiley and Sons
๐
English
โ 243 KB
๐ 1 views
Genetic screening of women from multiple-case breast cancer families and other research-based endeavors have identified an extensive collection of germline variations of BRCA1 and BRCA2 that can be classified as deleterious and have clinical relevance. For some variants, such as those in the conserv
Clinical characteristics and outcomes of
โ
Joyce Liu; Mihaela C. Cristea; Paul Frankel; Susan L. Neuhausen; Linda Steele; V
๐
Article
๐
2012
๐
Elsevier
๐
English
โ 301 KB