𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Brazilian P[8],G1, P[8],G5, P[8],G9, and P[4],G2 rotavirus strains: Nucleotide sequence and phylogenetic analysis

✍ Scribed by Irene Trigueiros Araújo; Rosane M. Santos Assis; Alexandre Madi Fialho; Joana D'Arc P. Mascarenhas; Marcos Bryan Heinemann; José Paulo G. Leite

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
127 KB
Volume
79
Category
Article
ISSN
0146-6615

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Rotavirus epidemiological surveys with molecular analysis of strains are required for gastroenteritis control and prevention. Twenty‐nine human rotavirus strains detected in Rio de Janeiro, Brazil, from 1986 to 2004 were characterized as P[8],G1, P[8],G5, P[8],G9, and P[4],G2 genotypes. The VP7 genes were sequenced and phylogenetic analysis was performed. Strains of genotype G1 revealed two distinct lineages, G1‐3 and G1‐4; strains of genotype G2 grouped in lineage G2‐1; G5 strains clustered with other Brazilians G5 strains and G9 strains were closely related to each other in lineage G9‐3, distinct from the original G9 strains detected in 1980s. The VP4 genes were analyzed and P[8] strains fell into two major genetic lineages, P[8]‐2 and P[8]‐3. Our findings document an intragenotype diversity represented by lineages and sublineages within rotavirus circulating in Rio de Janeiro from 1986 to 2004, before application of a vaccine (Rotarix®) in Brazil. This report emphasizes the importance of continuing monitor genotypes to verify if uncommon strains or newly strains are emerging to be specifically addressed in future vaccine trials. J. Med. Virol. 79:995‐1001, 2007. © 2007 Wiley‐Liss, Inc.

📜 SIMILAR VOLUMES

Detection of uncommon rotavirus a strain
Detection of uncommon rotavirus a strains P[8]G8 and P[4]G8 in the city of Rio de Janeiro, 2002
✍ M.M. Gómez; E.M. Volotão; M.C. Lima de Mendonça; L.F.L. Tort; M.F.M. da Silva; J 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 152 KB

## Abstract Group A rotaviruses (RV‐A) are the major cause of gastroenteritis in infants and young children around the world. Each year RV‐A causes approximately 11 million episodes of severe diarrhea, with an estimated of 611,000 deaths. Epidemiologic surveys have identified P[8]G1, P[4]G2, P[8]G3

Dominating prevalence of P[8],G1 and P[8
Dominating prevalence of P[8],G1 and P[8],G9 rotavirus strains among children admitted to hospital between 2000 and 2003 in Budapest, Hungary
✍ Krisztián Bányai; Jon R. Gentsch; Renáta Schipp; Ferenc Jakab; Edina Meleg; Ilon 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 201 KB

Group A rotaviruses are the main cause of acute dehydrating diarrhea in children, responsible for high mortality in developing countries and a significant socio-economic burden associated with treating the disease in developed countries. Two rotavirus vaccine candidates predicated on either homotypi

Sequencing and phylogenetic analysis of
Sequencing and phylogenetic analysis of the coding region of six common rotavirus strains: Evidence for intragenogroup reassortment among co-circulating G1P[8] and G2P[4] strains from the United States
✍ K. Bányai; S. Mijatovic-Rustempasic; J.J. Hull; M.D. Esona; M.M. Freeman; A.M. F 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 456 KB

## Abstract The segmented genome of rotaviruses provides an opportunity for rotavirus strains to generate a large genetic diversity through reassortment; however, this mechanism is considered to play little role in the generation of mosaic gene constellations between Wa‐like and DS‐1‐like strains i

Detection of human rotavirus G9P[8] stra
Detection of human rotavirus G9P[8] strains circulating in Argentina: Phylogenetic analysis of VP7 and NSP4 genes
✍ Juan A. Stupka; Gabriel I. Parra; Jorge Gómez; Juan Arbiza 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 120 KB

## Abstract During the surveillance of rotavirus strains that were circulating in Argentinean children from 2000 to 2004, seven rotaviruses were detected bearing the genotype combination G9P[8]. The molecular characterization of the VP7 and NSP4 genes and the RNA migration patterns support the hypo

Molecular epidemiology of group A rotavi
Molecular epidemiology of group A rotavirus in Buenos Aires, Argentina 2004–2007: Reemergence of G2P[4] and emergence of G9P[8] strains
✍ Laura E. Esteban; Rosana P. Rota; Jon R. Gentsch; Baoming Jiang; Mathew Esona; R 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 318 KB

## Abstract Detection and characterization of group A rotavirus in Buenos Aires, Argentina, was conducted on 710 fecal samples from children 0–15 years old collected between 2004 and 2007. Rotavirus was detected in 140 (19.7%) samples with G9P[8] (30.0%) and G2P[4] (21.4%) as the most common genoty

Rotavirus G and P types in children with
Rotavirus G and P types in children with acute diarrhea in Blantyre, Malawi, from 1997 to 1998: Predominance of novel P[6]G8 Strains
✍ Cunliffe, Nigel A.; Gondwe, Jailosi S.; Broadhead, Robin L.; Molyneux, Malcolm E 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 251 KB 👁 2 views

One hundred rotavirus strains detected in children with acute diarrhea in Blantyre, Malawi, between July 1997 and January 1998 were characterized for G (VP7) and P (VP4) types by using multiplex, heminested, reverse transcription-polymerase chain reaction. A novel P[6]G8 rotavirus strain was identif