✦ LIBER ✦
Brainstem glioma after radiation therapy for acute myeloblastic leukemia in a child with down syndrome. Possible pathogenetic mechanisms
✍ Scribed by David Zagzag; Douglas C. Miller; Joan Cangiarella; Jeffrey C. Allen; M. Alba Greco
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 822 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
✦ Synopsis
A 13-year-old boy with Down syndrome (DS) had a brainstem glioma confirmed at autopsy, 10 years after receiving prophylactic cranial irradiation for acute myeloblastic leukemia. There is no clear association of brain tumors with DS; despite a reported link between leukemia and glioma, a causal association with radiation therapy is more likely.