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Brain uptake and the analgesic effect of oxytocin— Its usefulness as an analgesic agent

✍ Scribed by Young-Sook Kang; Ji-Hyun Park


Publisher
Springer
Year
2000
Tongue
English
Weight
490 KB
Volume
23
Category
Article
ISSN
0253-6269

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Enzyme specificity and tissue distributi
✍ Shoji Takakura; Hideaki Minoura; Yukinori Shimoshige; Kyoko Minoura; Ikuo Kawamu 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 146 KB

## Abstract The enzyme specificity and tissue distribution of zenarestat, an aldose reductase inhibitor, was investigated in diabetic rats. Zenarestat inhibited both rat sciatic nerve aldose reductase (AR) activity and recombinant human AR with IC~50~ values of 7.5 and 44 nM, respectively. However,