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Brain tumors in infants: a study of 76 patients operated upon

✍ Scribed by C. Lapras; J. N. Guilburd; J. Guyotat; J. D. Patet

Book ID
104695553
Publisher
Springer
Year
1988
Tongue
English
Weight
358 KB
Volume
4
Category
Article
ISSN
0256-7040

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✦ Synopsis

Seventy-six children were studied who had been operated on for intracranial tumors; they ranged in age from 0 to 2 years. Twenty-nine cases were under 1 year and 47 between 1 and 2 years of age. The outlook was relatively poor regarding the highly malignant tumors, but surprisingly encouraging in benign and low-grade malignant neoplasms. The undesirable effects of complementary oncological treatment in this age category are stressed. On the other hand the importance of radical surgery is emphasized as the best treatment for these lesions.

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## Abstract ## BACKGROUND Fotemustine is a nitrosourea with theoretic and preclinical advantages over the original analogs, carmustine and lomustine, in the treatment of brain tumors. This is the first pediatric Phase I study of fotemustine. ## METHODS Patients younger than 21 with recurrent/res