✦ LIBER ✦

Brain tumors after cranial irradiation for childhood acute lymphoblastic leukemia. A 13-year experience from the Dana-Farber cancer institute and the children's hospital

✍ Scribed by Ilonna J. Rimm; Frederick C. Li; Nancy J. Tarbell; Ken R. Winston; Stephen E. Sallan

Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 294 KB
Volume: 59
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19870415)59:8<1506::aid-cncr2820590819>3.0.co;2-p

No coin nor oath required. For personal study only.

✦ Synopsis

Brain tumors developed in two children after they had received cranial irradiation as central nervous system therapy for acute lymphoblastic leukemia. A review of the literature demonstrated an increased incidence of brain tumors in survivors of acute lymphoblastic leukemia who received central nervous system irradiation. Most of the brain tumors occurred within a decade after radiotherapy. Further data will be required to determine whether early post-radiation brain tumors in patients with acute lymphoblastic leukemia are due to the central nervous system irradiation or to a genetic predisposition.

📜 SIMILAR VOLUMES

Excellent therapeutic efficacy and minim

Excellent therapeutic efficacy and minimal late neurotoxicity in children treated with 18 grays of cranial radiation therapy for high-risk acute lymphoblastic leukemia : A 7-year follow-up study of the dana-farber cancer institute consortium protocol 87-01

✍ Deborah P. Waber; Brenda L. Shapiro; Sarah C. Carpentieri; Richard D. Gelber; Gu 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 89 KB 👁 3 views

## Background: In the current study, the authors evaluated late neuropsychologic effects 7 years after diagnosis and the long-term survival in a cohort of patients treated for high-risk childhood acute lymphoblastic leukemia (all) with cranial radiation therapy. efficacy and toxicity were evaluated