Brain tissue pO2 and pCO2 levels before and after cerebral revascularization

✍ Scribed by Dr. Christopher B. Shields; Mr. Esther Roberts; Dr. Mitsuo Numoto

• Book ID: 102510552
• Publisher: John Wiley and Sons
• Year: 1980
• Tongue: English
• Weight: 453 KB
• Volume: 1
• Category: Article
• ISSN: 0738-1085
• DOI: 10.1002/micr.1920010404

✦ Synopsis

Microvascular surgical techniques have made possible the improvement of cerebral blood flow, as demonstrated by angiography and by regional cerebral blood flow research. In this study, simultaneous mass spectrometer determinations of brain tissue and blood PO, and pC0, levels were used to evaluate the effectiveness of common carotid-supraclinoid carotid anastomoses (CC-SCA) in dogs. With blood pC0, maintained at a constant level, the baseline brain tissue PO, and pC0, levels were recorded. During the CC-SCA procedure, which involved brain retraction and temporary vascular occlusion, brain tissue PO, levels fell to 40% of baseline and pCOz levels rose by 35%. Following restoration of flow via the anastomosis, the brain tissue PO, and pC0, levels again reached baseline.