Brain Repair

✍ Scribed by Kerstin Krieglstein (auth.), Mathias Bähr (eds.)

• Publisher: Springer US
• Year: 2006
• Tongue: English
• Leaves: 264
• Series: Advances in Experimental Medicine and Biology 557
• Edition: 1
• Category: Library

✦ Synopsis

Brain Repair, addresses all relevant issues underlying the mechanisms of brain damage, brain plasticity and post-traumatic reorganisation after CNS lesions. This book is divided the three major sections that follow; cellular and molecular basis of brain repair, plasticity and reorganisation of neural networks, and experimental therapy strategies.

Brain Repair is written by high profile, international experts who describe in detail the newest results from basic research and highlight new model systems, techniques and therapy approaches. Based on a careful analysis of the cellular and molecular reaction patterns of the CNS to lesions, the contributions cover possibilities for endogenous reorganisation and repair as well as exciting new therapies emerging from basic research, some of which have already been introduced into the clinics. Thus, this book is unique in bridging the gap between basic and clinical research. It will be a valuable tool for all students, researchers and clinicians interested in understanding the brain's capacity to cope with lesions and interested in learning about emerging new therapy concepts.

✦ Table of Contents

Cell Death in the Nervous System....Pages 1-10
The Glial Response to Injury and Its Role in the Inhibition of CNS Repair....Pages 11-24
DSD-1-Proteoglycan/Phosphacan and Receptor Protein Tyrosine Phosphatase-Beta Isoforms during Development and Regeneration of Neural Tissues....Pages 25-53
Regeneration Failure in the CNS....Pages 54-76
The Role of Ionotropic Purinergic Receptors (P2X) in Mediating Plasticity Responses in the Central Nervous System....Pages 77-100
Lesion-Induced Axonal Sprouting in the Central Nervous System....Pages 101-121
A Kinase with a Vision....Pages 122-132
Attempts to Restore Visual Function after Optic Nerve Damage in Adult Mammals....Pages 133-147
Brain Repair....Pages 148-163
Neuroprotection by cAMP....Pages 164-176
The Collagenous Wound Healing Scar in the Injured Central Nervous System Inhibits Axonal Regeneration....Pages 177-190
Role of Endogenous Neural Stem Cells in Neurological Disease and Brain Repair....Pages 191-220
Transplantation in Parkinson’s Disease....Pages 221-248

✦ Subjects

Neurosciences; Neurology; Neurosurgery; Biomedicine general; Pathology