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Brain norepinephrine and serotonin levels following REM sleep deprivation in the rat

✍ Scribed by Warren C. Stern; Francis P. Miller; Raymond H. Cox; Roger P. Maickel

Publisher
Springer
Year
1971
Tongue
English
Weight
335 KB
Volume
22
Category
Article
ISSN
0033-3158

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✦ Synopsis

Rats deprived of rapid eye movement (REM) sleep and stress controls showed no change in endogenous levels of norepinephrine and serotonin in the cerebral hemispheres, dieneephalon, and brain stem. Following pargyline, the REM sleep deprived and stress control groups showed equally elevated norepinephrine and serotonin levels. These results suggest that enhanced biogenic amine synthesis following REM sleep deprivation is due to non specific stress rather than to loss of REM sleep per se.

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