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Brain monoamines metabolism in transgenic mice expressing high levels of human neuronal monoamine oxidase B

โœ Scribed by E. Borroni; J. Gottowik; A. Cesura; P. Malherbe; M. Da Prada


Book ID
119179713
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
146 KB
Volume
31
Category
Article
ISSN
1043-6618

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## Abstract The effect of a lack of the gene encoding monoamine oxidase A (MAO A) in transgenic Tg8 mice on the activity of tryptophan hydroxylase (TPH), the rateโ€limiting enzyme in serotonin (5โ€HT) biosynthesis, and on the levels of 5โ€HT and 5โ€hydroxyindoleacetic acid (5โ€HIAA) in the midbrain, hyp