Frequent EGFR mutations in brain metasta
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Shingo Matsumoto; Kenji Takahashi; Reika Iwakawa; Yoshihiro Matsuno; Yukihiro Na
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Article
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2006
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John Wiley and Sons
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French
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## Abstract Lung adenocarcinomas often metastasize to the brain, and the prognosis of patients with brain metastases is still very poor. The __epidermal growth factor receptor__ (__EGFR__) gene is mutated in a considerable fraction of primary lung adenocarcinomas, in particular those with drastic r