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Brain-Derived Neurotrophic Factor Signaling and Subgenual Anterior Cingulate Cortex Dysfunction in Major Depressive Disorder

✍ Scribed by Tripp, Adam; Oh, Hyunjung; Guilloux, Jean-Philippe; Martinowich, Keri; Lewis, David A.; Sibille, Etienne

Book ID: 118170140
Publisher: American Psychiatric Publishing Inc
Year: 2012
Tongue: English
Weight: 638 KB
Volume: 169
Category: Article
ISSN: 0002-953X
DOI: 10.1176/appi.ajp.2012.12020248

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Recent studies have implicated brain-derived neurotrophic factor (BDNF) in the pathophysiology of depression and in the activities of antidepressant drugs. Serum BDNF levels are lower in depressed patients and increase in response to antidepressant medications; however, no studies have examined the