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Brain-Derived Neurotrophic Factor Protects Against Ischemic Cell Damage in Rat Hippocampus

✍ Scribed by Beck, Thomas; Lindholm, Dan; Castren, Eero; Wree, Andreas


Book ID
109870828
Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
451 KB
Volume
14
Category
Article
ISSN
0271-678X

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Hydrophobic dipeptide Leu-Ile protects a
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## Abstract We investigated whether certain hydrophobic dipeptides, Leu‐Ile, Leu‐Pro, and Pro‐Ile, which partially resemble the site on FK506 that binds to immunophilin, could stimulate glial cell line‐derived neurotrophic factor (GDNF) and brain‐derived neurotrophic factor (BDNF) synthesis in cult