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Brain-derived neurotrophic factor promotes axonal regeneration and long-term survival of adult rat spinal motoneurons in vivo

โœ Scribed by L Novikov; L Novikova; J.-O Kellerth


Book ID
117491725
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
581 KB
Volume
79
Category
Article
ISSN
0306-4522

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Adult rat retinal ganglion cells (RGC) undergo degeneration after optic nerve transection. Studies have shown that exogenously applied neurotrophic factors such as brain-derived neurotrophic factor (BDNF) can attenuate axotomy-induced as well as developmental RGC death. Here, we examined whether gli