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Brain-derived neurotrophic factor modulates dopaminergic deficits in a transgenic mouse model of Huntington's disease

✍ Scribed by José R. Pineda; Josep M Canals; Miquel Bosch; Albert Adell; Guadalupe Mengod; Francesc Artigas; Patrik Ernfors; Jordi Alberch

Book ID
111178821
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
525 KB
Volume
93
Category
Article
ISSN
0022-3042

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## Abstract Huntington's disease (HD) is a neurodegenerative disorder characterized by motor, cognitive, and psychiatric symptoms and by a progressive degeneration of neurons in basal ganglia and in brain cortex. Brain‐derived neurotrophic factor (BDNF) is a pro‐survival factor for striatal neurons