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Brain Derived Neurotrophic Factor (BDNF) gene variants association with age at onset and therapeutic response in schizophrenia

โœ Scribed by Krebs, M O; Guillin, O; Bourdel, M C; Schwartz, J C; Olie, J P; Poirier, M F; Sokoloff, P


Book ID
110059212
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
115 KB
Volume
5
Category
Article
ISSN
1359-4184

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## Abstract Several lines of evidence indicate an involvement of brain derived neurotrophic factor (BDNF) in body weight regulation and activity: heterozygous __Bdnf__ knockout mice (__Bdnf__^+/โˆ’^) are hyperphagic, obese, and hyperactive; furthermore, central infusion of BDNF leads to severe, doseโ€