Brain-Derived Neurotrophic Factor and trkB Receptor mRNAs in Grafts of Cortex Cerebri
β Scribed by Christian Humpel; Maibritt M.J. Giacobini; Cynthia Wetmore; Lars Olson
- Book ID
- 115606128
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 701 KB
- Volume
- 127
- Category
- Article
- ISSN
- 0014-4886
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Although neurotrophins are critical for neuronal survival and differentiation, recent studies suggest that they also regulate synaptic plasticity. Brain-derived neurotrophic factor (BDNF) rapidly increases synaptic transmission in hippocampal neurons, and enhances long-term potentiation (LTP), a cel
## Abstract The effects of transforming growth factor (TGF)βΞ²1 on expression of brainβderived neurotrophic factor (BDNF) and its highβaffinity receptor, TrkB, in neurons cultured from the cerebral cortex of 18βdayβold embryonic rats were examined. BDNF mRNA was significantly increased from 24β48 hr