L-ornithine phenylacetate attenuates inc
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Lars Marius YtrebΓΈ; Rune GangsΓΈy Kristiansen; Hanne MΓ¦hre; Ole Martin FuskevΓ₯g;
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Article
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2009
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John Wiley and Sons
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English
β 900 KB
Hyperammonemia is a feature of acute liver failure (ALF), which is associated with increased intracranial pressure (ICP) and brain herniation. We hypothesized that a combination of L-ornithine and phenylacetate (OP) would synergistically reduce toxic levels of ammonia by (1) L-ornithine increasing g