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Brain cytokine flux in acute liver failure and its relationship with intracranial hypertension

✍ Scribed by Gavin Wright; Debbie Shawcross; Steven W. M. Olde Damink; Rajiv Jalan


Book ID
106459952
Publisher
Springer
Year
2007
Tongue
English
Weight
405 KB
Volume
22
Category
Article
ISSN
0885-7490

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L-ornithine phenylacetate attenuates inc
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Hyperammonemia is a feature of acute liver failure (ALF), which is associated with increased intracranial pressure (ICP) and brain herniation. We hypothesized that a combination of L-ornithine and phenylacetate (OP) would synergistically reduce toxic levels of ammonia by (1) L-ornithine increasing g