Brain Creatine Kinase with Aging in F-344 Rats: Analysis by Saturation Transfer Magnetic Resonance Spectroscopy

Combining CW and pulsed saturation allow

Combining CW and pulsed saturation allows in vivo quantitation of magnetization transfer observed for total creatine by 1H-NMR-spectroscopy of rat brain

✍ Stefan A. Roell; Wolfgang Dreher; Dieter Leibfritz 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 144 KB 👁 2 views

Selective saturation of bound nuclei attenuates the MR visible CH 2 and the CH 3 signal of total creatine (tCr) in rat brain in vivo. The low contrast to noise ratio achieved during the limited experiment time makes it difficult to quantify the effect. It is shown that by combining data from continu