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Brain benzodiazepine receptor binding and purine concentration in Lesch-Nyhan syndrome

✍ Scribed by Stephen J. Kish; Irving H. Fox; Bhushan M. Kapur; Kenneth Lloyd; Oleh Hornykiewicz


Book ID
118022794
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
575 KB
Volume
336
Category
Article
ISSN
0006-8993

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Human lymphoblasts derived from normal and hypoxanthine-guanine phos-phoribosyItransferase (HGPRT) deficient individuals have been maintained in permanent tissue culture, and comparative studies of their purine metabolism have been undertaken. In agreement with previous observations in fibroblasts,