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BRAF Mutation is associated with early stage disease and improved outcome in patients with low-grade serous ovarian cancer

✍ Scribed by Rachel N. Grisham; Gopa Iyer; Karuna Garg; Deborah DeLair; David M. Hyman; Qin Zhou; Alexia Iasonos; Michael F. Berger; Fanny Dao; David R. Spriggs; Douglas A. Levine; Carol Aghajanian; David B. Solit


Book ID
115554722
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
463 KB
Volume
119
Category
Article
ISSN
0008-543X

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Phosphorylated AKT expression is associa
✍ Yoshifumi Baba; Katsuhiko Nosho; Kaori Shima; Marika Hayashi; Jeffrey A. Meyerha πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 357 KB πŸ‘ 1 views

## Abstract ## BACKGROUND: AKT (AKT1, AKT2, and AKT3) was a downstream effector of phosphatidylinositide‐3‐kinase (PI3K) and played crucial roles in protein synthesis, cellular metabolism, survival, and proliferation. The PI3K/AKT pathway was commonly activated in human cancers and was recognized