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Bradykinin Stimulates Phosphoinositide Hydrolysis and Mobilization of Arachidonic Acid in Dorsal Root Ganglion Neurons

โœ Scribed by Charles M. Gammon; Ann C. Allen; Pierre Morell

Book ID
111175117
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
853 KB
Volume
53
Category
Article
ISSN
0022-3042

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Bradykinin and capsaicin stimulate cycli
Bradykinin and capsaicin stimulate cyclic GMP production in cultured rat dorsal root ganglion neurons via a nitrosyl intermediate
โœ M. B. Bauer; M. L. Simmons; S. Murphy; G. F. Gebhart ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 901 KB

Dorsal root ganglion (DRG) neurons express receptors for bradykinin and capsaicin, both algesic substances. Administration of bradykinin or capsaicin to neurons cultured from embryonic rat DRG stimulated the production of cyclic GMP but did not affect the production of cyclic GMP in nonneuronal DRG