The history of interstitial brachytherapy of the prostate began in 1917 when Barringer inserted radium needles transperineally into the prostate, guided by a finger in the rectum. In 1952, Flocks et al. injected radioactive gold solution in prostatic cancer during open operation. In 1972, Whitmore e
Brachytherapy in cancer of the prostate: An historical perspective
โ Scribed by Basil S. Hilaris
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 212 KB
- Volume
- 13
- Category
- Article
- ISSN
- 8756-0437
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โฆ Synopsis
Carcinoma of the prostate in the United States has increased dramatically in the last few years due to improved detection methods including prostatic specific antigen testing and transrectal ultrasound. More than half of all prostate cancers are discovered while still localized. Radical prostatectomy and definitive radiation are reserved for patients in good health, who have localized disease. Brachytherapy, with its inherent ability to deliver a high dose to an organconfined tumor, while minimally irradiating the surrounding tissues, has successfully competed with external beam for the treatment of early prostatic tumors. Their respective role is constantly under scrutiny and re-evaluation to improve the accuracy of delivery of radiation. The present review focuses on the role of brachytherapy for treatment of early cancer of the prostate over the span of this century and its future in the next millennium.
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Prostate cancer is the most commonly diagnosed malignancy among men in the United States. Radical prostatectomy has been the gold standard for treating clinically localized prostate cancer. Its morbidity and disease-control capabilities have been well studied. At 10 years after surgery, 50% to 70% o
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