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Bovine Fetal Hemoglobin. I. Postnatal Persistence and Relation to Adult Hemoglobins

✍ Scribed by Grimes, R.M.; Duncan, C.W.; Lassiter, C.A.


Book ID
122596294
Publisher
American Dairy Science Association
Year
1958
Tongue
English
Weight
909 KB
Volume
41
Category
Article
ISSN
0022-0302

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Some types of nondeletional heterocellular hereditary persistence of fetal hemoglobin (HPFH) appear to be caused by mutations in the beta globin gene cluster near the gamma globin genes, while in other cases the condition is associated with a gene or genes outside the beta globin gene complex. We ha

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A variant of fetal hemoglobin (Hb F-Malta-I) has been detected and quantitated in adult blood with a sensitive radioimmunoassay employing monospecific antisera. The concentration of Hb-F-Malta-I was 0.002-0.05%, with an average value of 0.011%. The ratio of Hb F-Malta-I/Hb F in adults was about 4.8%