Botulinum toxin type-a in therapy of patients with anismus
β Scribed by Y. Ron; Y. Avni; A. Lukovetski; J. Wardi; D. Geva; S. Birkenfeld; Z. Halpern
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 550 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0012-3706
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## Abstract In some patients, therapy with botulinum toxin type A (BTβA) becomes ineffective due to formation of antibodies (BTβAβAB). The time course of BTβAβAB titres after cessation of BTβA therapy was quantitatively studied to determine whether and when they might drop. Thirteen patients (eight
## Abstract Fifteen patients with torticollis who had been treated with repeated injections of botulinum toxin type A (botox A) developed antibodies to the toxin. This resulted in loss of benefit in the 13 patients who had improved with botox A injections and failure to develop muscle atrophy after
## Abstract Between 1984 and 1992, 559 patients with torticollis were treated with botulinum toxin type A (btx) injections. Twentyβfour of these 559 patients (4.3%) had serological evidence of antibodies to btx by mouse neutralization assay. Some of the 559 patients had only one or two injection se
## Abstract Intramuscular injection of botulinum toxin type A is the treatment of choice for most cases of oromandibular dystonia. We report on five patients with oromandibular dystonia that developed secondary nonresponsiveness to botulinum toxin type A following multiple injections over a 6βyear