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Botulinum neurotoxin serotype A: A new tool for inflammatory and neuropathic pain

✍ Scribed by Luvisetto Siro; Marinelli Sara; Cobianchi Stefano; Pavone Flaminia

Book ID
116922168
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
53 KB
Volume
51
Category
Article
ISSN
0041-0101

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Botulinum neurotoxins (BoNT) are zinc metalloproteases that cleave and inactivate cellular proteins essential for neurotransmitter release. Because the paralytic effect of BoNT is a consequence of its enzymatic activity, selective inhibitors may be useful as drugs or as tools for further research. T