Both N-ras and c-myc are activated in the shac human stomach fibrosarcoma cell line

miR-520c and miR-373 upregulate MMP9 exp

miR-520c and miR-373 upregulate MMP9 expression by targeting mTOR and SIRT1, and activate the Ras/Raf/MEK/Erk signaling pathway and NF-κB factor in human fibrosarcoma cells

✍ Ping Liu; Michael J. Wilson 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 721 KB

## Abstract MicroRNA 520c and 373 (miR‐520c and miR‐373) have been characterized as oncogenes and play critical roles in cancer cell metastasis. However, the relationship between these two microRNAs and matrix metalloproteinases (MMPs), which are important in cancer cell metastasis, remains unknown