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Both Epidermal Growth Factor-Like Domains of the Merozoite Surface Protein-1 from Plasmodium yoelii Are Required for Protection from Malaria

✍ Scribed by PAUL A. CALVO; THOMAS M. DALY; CAROLE A. LONG


Book ID
119873690
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
140 KB
Volume
797
Category
Article
ISSN
0890-6564

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## Abstract The __Plasmodium falciparum__ merozoite surface protein‐1 19 kDa fragment (MSP‐1~19~) comprises two closely packed EGF‐like domains (EGF=epidermal growth factor), each stabilized by three disulfide bonds. The native conformation of this protein is important for eliciting __P. falciparum