Both Enantiomers of N-Boc-indoline-2-carboxylic Esters.
✍ Scribed by Masayuki Kurokawa; Takeshi Sugai
- Book ID
- 101965608
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 142 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Both enantiomers of 2‐__tert__‐butyl‐2‐methyl‐1,3‐benzodioxole‐4‐carboxylic (TBMB) acid, which has a unique quaternary chiral center located on the acetal carbon, were prepared from a racemic ketone in which the carboxy group was replaced by a trifluoroacetyl group. First, reduction wit