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Both copy number and sequence variation determine expression of human DEFB4

✍ Scribed by K. Huse; M. Groth; C. Wiegand; K. Szafranski; P. Rosenstiel; S. Schreiber


Book ID
104064775
Publisher
Elsevier
Year
2010
Tongue
English
Weight
77 KB
Volume
27
Category
Article
ISSN
1871-6784

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## Abstract Previous low‐resolution studies of chromosome 22 in ovarian carcinoma have suggested its involvement in the development of the disease. We report a high‐resolution analysis of DNA copy number and gene expression of 22q in 18 ovarian carcinomas using a 22q‐specific genomic microarray. We