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Bostrycin inhibits proliferation of human lung carcinoma A549 cells via downregulation of the PI3K/Akt pathway

✍ Scribed by Wei-Sheng Chen; Jun-Na Hou; Yu-Biao Guo; Hui-Ling Yang; Can-Mao Xie; Yong-Cheng Lin; Zhi-Gang She

Book ID: 119913679
Publisher: BioMed Central
Year: 2011
Tongue: English
Weight: 618 KB
Volume: 30
Category: Article
ISSN: 1756-9966
DOI: 10.1186/1756-9966-30-17

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## Abstract Angiogenesis plays a crucial role in tumor growth and metastases. The extent of angiogenesis correlates with the increased invasion and metastasis in a variety of human neoplasms. Vascular endothelial cell proliferation and migration are critical steps in angiogenesis and are regulated