## Abstract 2‐Thiopyridone (2‐mercaptopyridine, **1**) was found to be a very suitable reagent for removing the __N__^α^‐o‐nitrophenylsulfenyl (NPS‐) group in both conventional and solid‐support peptide synthesis. A 3‐ to 5‐molar excess of the reagent together with an equivalent amount of glacial a
✦ LIBER ✦
Boron Tris(trifluoroacetate) for Removal of Protecting Groups in Peptide Chemistry
✍ Scribed by Dr. J. Pless; W. Bauer
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- English
- Weight
- 238 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0044-8249
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## Abstract The value of several reagents capable of removing quantitatively the α‐amino protecting group of NPS‐aminoacyl‐ or peptidyl‐derivatives is assessed, by comparison with the reagents currently used, __i.e.__ hydrogen chloride, RS^–^‐nucleophiles or alkyl thioamides, especially with regard