Boron trifluoride catalysed reactions of 2,2,2-trichloroethyl-6-diazopenicillanate with ketones: preparation of novel 6β-acyl-6α-alkyl(aryl) penicillanates.

✍ Scribed by V.J. Jephcote; D.I. John

• Publisher: Elsevier Science
• Year: 1984
• Tongue: French
• Weight: 230 KB
• Volume: 25
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)81326-5

✦ Synopsis

The BF3.Et20 catalysed reactions of the diazopenicillanate 1 with ketones provide novel 6-acyl-6-alkyl(aryl)penicillanates 2, together with thiazolooxazinones 6 formed via penam C(5)-C(6) cleavage reactions.