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Boron-containing nucleic acids. Synthesis of cyanoborane adducts of 2'-deoxynucleosides

✍ Scribed by Sood, Anup; Shaw, Barbara Ramsay; Spielvogel, Bernard F.

Book ID
120528139
Publisher
American Chemical Society
Year
1989
Tongue
English
Weight
281 KB
Volume
111
Category
Article
ISSN
0002-7863

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## Abstract We have developed a simple and convenient synthetic strategy for the preparation of tetrahydropyranyl, 4‐methoxytetrahydropyranyl, and tetrahydrofuranyl ethers of 2′‐deoxynucleosides, which are useful building blocks for nucleic acid chemistry. Enzymatic benzoylation provides an efficie